Structure of PDB 1scj Chain A

Receptor sequence
>1scjA (length=275) Species: 1423 (Bacillus subtilis) [Search protein sequence]
AQSVPYGISQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDLNVRGGASF
VPSETNPYQDGSSHGTHVAGTIAALNNSIGVLGVSPSASLYAVKVLDSTG
SGQYSWIINGIEWAISNNMDVINMSLGGPTGSTALKTVVDKAVSSGIVVA
AAAGNEGSSGSTSTVGYPAKYPSTIAVGAVNSSNQRASFSSAGSELDVMA
PGVSIQSTLPGGTYGAYNGTCMATPHVAGAAALILSKHPTWTNAQVRDRL
ESTATYLGNSFYYGKGLINVQAAAQ
3D structure
PDB1scj The crystal structure of an autoprocessed Ser221Cys-subtilisin E-propeptide complex at 2.0 A resolution.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D32 H64 N155 C221
Catalytic site (residue number reindexed from 1) D32 H64 N155 C221
Enzyme Commision number 3.4.21.62: subtilisin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A Q2 D41 L75 N77 I79 V81 Q2 D41 L75 N77 I79 V81
BS02 CA A A169 Y171 T174 A176 A169 Y171 T174 A176
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1scj, PDBe:1scj, PDBj:1scj
PDBsum1scj
PubMed9811547
UniProtP04189|SUBT_BACSU Subtilisin E (Gene Name=aprE)

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