Structure of PDB 1sbr Chain A

Receptor sequence
>1sbrA (length=182) Species: 1423 (Bacillus subtilis) [Search protein sequence]
RIAGFRFSLYPMTDDFISVIKSALAATDTSKVWTKTDHISTVLRGSIDHV
FDAAKAIYLHAANSEQHIVMNGTFSIGCPGDTQGDTYLKRVNEDAVRGLK
AEAPCQFALYPMNEPDYMGLIMEAVDIAKAQGTFVQGVHYASELDGDAHD
VFSTLEAVFRMAEQQTNHITMTVNLSANSPSR
3D structure
PDB1sbr The Structure and Ligand Binding Properties of the B.subtilis YkoF Gene Product, a Member of a Novel Family of Thiamin/HMP-binding Proteins
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A A33 T35 A25 T27
BS02 VIB A F15 S16 L17 D45 H46 I47 S48 T49 F7 S8 L9 D37 H38 I39 S40 T41 MOAD: Kd~10uM
PDBbind-CN: -logKd/Ki=5.00,Kd=10uM
BS03 VIB A F119 A120 L121 M130 I133 S154 F107 A108 L109 M118 I121 S142 MOAD: Kd~10uM
PDBbind-CN: -logKd/Ki=5.00,Kd=10uM
Gene Ontology
Molecular Function
GO:0030975 thiamine binding

View graph for
Molecular Function
External links
PDB RCSB:1sbr, PDBe:1sbr, PDBj:1sbr
PDBsum1sbr
PubMed15451668
UniProtO34911|YKOF_BACSU Putative HMP/thiamine-binding protein YkoF (Gene Name=ykoF)

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