Structure of PDB 1sax Chain A

Receptor sequence
>1saxA (length=120) Species: 158879 (Staphylococcus aureus subsp. aureus N315) [Search protein sequence]
NKTYEISSAEWEVMNIIWMKKYASANNIIEEIQMQKDWSPKTIRTLITRL
YKKGFIDRKKDNKIFQYYSLVEESDIKYKTSKNFINKVYKGGFNSLVLNF
VEKEDLSQDEIEELRNILNK
3D structure
PDB1sax On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R46 R60 I66 F67 R44 R58 I64 F65
BS02 dna A K4 E7 S9 S10 A11 S41 K43 T44 T47 R51 K2 E5 S7 S8 A9 S39 K41 T42 T45 R49
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription
GO:0046677 response to antibiotic
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1sax, PDBe:1sax, PDBj:1sax
PDBsum1sax
PubMed14960592
UniProtP68261|MECI_STAAN Methicillin resistance regulatory protein MecI (Gene Name=mecI)

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