Structure of PDB 1s9v Chain A

Receptor sequence
>1s9vA (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
VADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYVDLGRKETVWCLPVLRQ
FRFDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSKSPVTLGQ
PNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYL
TLLPSAEESYDCKVEHWGLDKPLLKHWEP
3D structure
PDB1s9v Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
ChainA
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A F51 R52 F54 F58 N62 V65 L66 N69 F51 R52 F53 F57 N61 V64 L65 N68
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:1s9v, PDBe:1s9v, PDBj:1s9v
PDBsum1s9v
PubMed15020763
UniProtP01909|DQA1_HUMAN HLA class II histocompatibility antigen, DQ alpha 1 chain (Gene Name=HLA-DQA1)

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