Structure of PDB 1s8e Chain A

Receptor sequence
>1s8eA (length=333) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence]
MKFAHLADIHLGYEQFHKPQREEEFAEAFKNALEIAVQENVDFILIAGDL
FHSSRPSPGTLKKAIALLQIPKEHSIPVFAIEGNLVRTQRGPSVLNLLED
FGLVYVIGMRKEKVENEYLTSERLGNGEYLVKGVYKDLEIHGMKYMSSAW
FEANKEILKRLFRPTDNAILMLHQGVREVSEARGEDYFEIGLGDLPEGYL
YYALGHIHKRYETSYSGSPVVYPGSLERWDFGDYEVRYEWDGIKFKERYG
VNKGFYIVEDFKPRFVEIKVRPFIDVKIKGSEEEIRKAIKRLIPLIPKNA
YVRLNIGWRKPFDLTEIKELLNVEYLKIDTWRI
3D structure
PDB1s8e Structural and functional analysis of Mre11-3
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D49 N84 H173 H206 D49 N84 H173 H206
BS02 MN A D8 H10 D49 H208 D8 H10 D49 H208
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Biological Process
GO:0000729 DNA double-strand break processing

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Molecular Function
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Biological Process
External links
PDB RCSB:1s8e, PDBe:1s8e, PDBj:1s8e
PDBsum1s8e
PubMed15047855
UniProtQ8U1N9|MRE11_PYRFU DNA double-strand break repair protein Mre11 (Gene Name=mre11)

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