Structure of PDB 1s6m Chain A

Receptor sequence

>1s6mA (length=288) Species: 562 (Escherichia coli) [Search protein sequence]

MLSHMVLTRQDIGRAASYYEDGADDYDASEWQGKGAEELGLSGEVDSKRF
RELLAGNIGEGHRIMRSATRQDSKERIGLDLTFSAPKSVSLQALVAGDAE
IIKAHDRAVARTLEQAEARAQARQKIQGKTRIETTGNLVIGKFRHETSRE
RDPQLHTHAVILNMTKRSDGQWRALKNDEIVKATRYLGAVYNAELAHELQ
KLGYQLRYGKDGNFDLAHIDRQQIEGFSKRTEQIAEWYAARGLDPNSVSL
EQKQAAKVLSRAKKTSVDREALRAEWQATAKELGIDFS

3D structure

PDB

1s6m Unveiling the molecular mechanism of a conjugative relaxase: The structure of TrwC complexed with a 27-mer DNA comprising the recognition hairpin and the cleavage site.

Chain

Resolution

2.28 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	M1 H4 M5 R14 A73 R75 Q76 K79 R81 S89 A90 K92 R128 Q129 K130 Q132 Q159 R172 R178 A179 N182 D183 R226 S233 R235 T236 K258 K262	M1 H4 M5 R14 A68 R70 Q71 K74 R76 S84 A85 K87 R123 Q124 K125 Q127 Q154 R167 R173 A174 N177 D178 R221 S228 R230 T231 K253 K257

External links

PDB	RCSB:1s6m, PDBe:1s6m, PDBj:1s6m
PDBsum	1s6m
PubMed	16540117
UniProt	Q47673

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