Structure of PDB 1s60 Chain A

Receptor sequence
>1s60A (length=152) [Search protein sequence]
LVPRGSHMDIRQMNKTHLEHWRGLRKQLWPGHPDDAHLADGEEILQADHL
ASFIAMADGVAIGFADASIRHDYVNGCDSSPVVFLEGIFVLPSFRQRGVA
KQLIAAVQRWGTNKGCREMASDTSPENTISQKVHQALGFEETERVIFYRK
RC
3D structure
PDB1s60 A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.82: aminoglycoside 6'-N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A I81 F82 V83 R88 Q89 G91 A93 K94 I122 V126 A129 I88 F89 V90 R95 Q96 G98 A100 K101 I129 V133 A136
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0042803 protein homodimerization activity
GO:0047663 aminoglycoside 6'-N-acetyltransferase activity
Biological Process
GO:0006084 acetyl-CoA metabolic process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:1s60, PDBe:1s60, PDBj:1s60
PDBsum1s60
PubMed15123251
UniProtQ9R381|AAC6_SALEN Aminoglycoside N(6')-acetyltransferase type 1

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