Structure of PDB 1s0h Chain A

Receptor sequence

>1s0hA (length=141) Species: 9793 (Equus asinus)

VLSAADKTNVKAAWSKVGGNAGEFGAEALERMFLGFPTTKTYFPHFDLSH
GSAQVKAHGKKVGDALTLAVGHLDDLPGALSNLSDLHAHKLRVDPVNFKL
LSHCLLSTLAVHLPNDFTPAVHASLDKFLSSVSTVLTSKYR

3D structure

• PDB: 1s0h Crystal structure of haemoglobin from donkey (Equus asinus) at 3A resolution
• Chain: A
• Resolution: 3.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	A	F43 H45 K61 L83 L86 H87 L91 V93 N97 F98 L136	F43 H45 K61 L83 L86 H87 L91 V93 N97 F98 L136

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0005506 iron ion binding
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex
• GO:0072562 blood microparticle

External links

• PDB: RCSB:1s0h, PDBe:1s0h, PDBj:1s0h
• PDBsum: 1s0h
• PubMed: 16488065
• UniProt: P01959|HBA_EQUAS Hemoglobin subunit alpha (Gene Name=HBA1)