Structure of PDB 1ryh Chain A

Receptor sequence
>1ryhA (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]
GSMQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDG
KPVNLGLWDTAGIADVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPII
LVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALT
QRGLKTVFDEAIRAVLCPPPV
3D structure
PDB1ryh Alternative Splicing of Rac1 Generates Rac1b, a Self-activating GTPase
ChainA
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A A13 G15 K16 T17 C18 F28 K135 D137 L138 S177 A178 L179 A15 G17 K18 T19 C20 F30 K105 D107 L108 S147 A148 L149 PDBbind-CN: -logKd/Ki=7.56,Kd=27.6nM
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007264 small GTPase-mediated signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:1ryh, PDBe:1ryh, PDBj:1ryh
PDBsum1ryh
PubMed14625275
UniProtP63000|RAC1_HUMAN Ras-related C3 botulinum toxin substrate 1 (Gene Name=RAC1)

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