Structure of PDB 1rxz Chain A

Receptor sequence
>1rxzA (length=245) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence]
MIDVIMTGELLKTVTRAIVALVSEARIHFLEKGLHSRAVDPANVAMVIVD
IPKDSFEVYNIDEEKTIGVDMDRIFDISKSISTKDLVELIVEDESTLKVK
FGSVEYKVALIDPSAIRKEPRIPELELPAKIVMDAGEFKKAIAAADKISD
QVIFRSDKEGFRIEAKGDVDSIVFHMTETELIEFNGGEARSMFSVDYLKE
FCKVAGSGDLLTIHLGTNYPVRLVFELVGGRAKVEYILAPRIESE
3D structure
PDB1rxz Structural Basis for FEN-1 Substrate Specificity and PCNA-Mediated Activation in DNA Replication and Repair
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A N43 V44 M46 P120 R121 P123 M192 Y219 P220 A239 P240 R241 I242 E243 S244 N43 V44 M46 P120 R121 P123 M192 Y219 P220 A239 P240 R241 I242 E243 S244
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030337 DNA polymerase processivity factor activity
Biological Process
GO:0006260 DNA replication
GO:0006272 leading strand elongation
GO:0006275 regulation of DNA replication

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1rxz, PDBe:1rxz, PDBj:1rxz
PDBsum1rxz
PubMed14718165
UniProtO29912|PCNA_ARCFU DNA polymerase sliding clamp (Gene Name=pcn)

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