Structure of PDB 1rsg Chain A

Receptor sequence
>1rsgA (length=481) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
PAKKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQ
GRKYDIGASWHHDTLTNPLFLEEAQLSLNDGRTRFVFDDDNFIYIDEERG
RVDHDKELLLEIVDNEMSKFAELEFDCSFFQLVMKYLLQRRQFLTNDQIR
YLPQLCRYLELWHGLDWKLLSAKDTYFGHQGRNAFALNYDSVVQRIAQSF
PQNWLKLSCEVKSITREPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSV
QPEKNLRGRIEFQPPLKPVIQDAFDKIHFGALGKVIFEFEECCWSNESSK
IVTLANSTNEFVEIVRNAENLDELDSMLSVTCWSQPLFFVNLSKSTGVAS
FMMLMQAPLTNHIESIREDKERLFSFFQPVLNKIMKCLDSEDVIDGMRAN
KPVLRNIIVSNWTRDPYSRGAYSACFPVDMVVAMSNGQDSRIRFAGEHTI
MDGAGCAYGAWESGRREATRISDLLKLEHHH
3D structure
PDB1rsg Crystal structures of fms1 and its complex with spermine reveal substrate specificity.
ChainA
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H67
Catalytic site (residue number reindexed from 1) H62
Enzyme Commision number 1.5.3.17: non-specific polyamine oxidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G15 G17 A19 E39 A40 R41 G46 R47 G62 A63 S64 W65 H67 V223 V253 G270 L294 W440 G478 E479 G487 C488 A489 A492 G10 G12 A14 E34 A35 R36 G41 R42 G57 A58 S59 W60 H62 V211 V241 G258 L282 W412 G446 E447 G455 C456 A457 A460
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0016491 oxidoreductase activity
GO:0046592 polyamine oxidase activity
GO:0050660 flavin adenine dinucleotide binding
GO:0052897 N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity
GO:0052901 spermine oxidase activity
GO:0052903 N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity
Biological Process
GO:0006338 chromatin remodeling
GO:0015940 pantothenate biosynthetic process
GO:0046208 spermine catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1rsg, PDBe:1rsg, PDBj:1rsg
PDBsum1rsg
PubMed15843025
UniProtP50264|FMS1_YEAST Polyamine oxidase FMS1 (Gene Name=FMS1)

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