Structure of PDB 1rrv Chain A

Receptor sequence
>1rrvA (length=401) Species: 31958 (Amycolatopsis orientalis) [Search protein sequence]
MRVLLSVCGTRGDVEIGVALADRLKALGVQTRMCAPPAAEERLAEVGVPH
VPVGLPQHMMLQEGMPPPPPEEEQRLAAMTVEMQFDAVPGAAEGCAAVVA
VGDLAAATGVRSVAEKLGLPFFYSVPSPVYLASPHLPPAYDEPTTPGVTD
IRVLWEERAARFADRYGPTLNRRRAEIGLPPVEDVFGYGHGERPLLAADP
VLAPLQPDVDAVQTGAWLLSDERPLPPELEAFLAAGSPPVHIGFGSSSGR
GIADAAKVAVEAIRAQGRRVILSRGWTELVLPDDRDDCFAIDEVNFQALF
RRVAAVIHHGSAGTEHVATRAGVPQLVIPRNTDQPYFAGRVAALGIGVAH
DGPTPTFESLSAALTTVLAPETRARAEAVAGMVLTDGAAAAADLVLAAVG
R
3D structure
PDB1rrv Crystal Structure of Vancosaminyltransferase Gtfd from the Vancomycin Biosynthetic Pathway: Interactions with Acceptor and Nucleotide Ligands
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.322: devancosaminyl-vancomycin vancosaminetransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A C8 G9 T10 M60 L61 Q62 M65 P67 L76 T80 D141 P143 N331 T332 C8 G9 T10 M60 L61 Q62 M65 P67 L76 T80 D141 P143 N331 T332
BS02 TYD A T10 G12 E15 S246 E293 V294 F296 H309 S311 G313 T314 T10 G12 E15 S246 E293 V294 F296 H309 S311 G313 T314
BS03 BGC A D13 G102 D103 D13 G102 D103
Gene Ontology
Molecular Function
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0017000 antibiotic biosynthetic process
GO:0030259 lipid glycosylation
GO:0033072 vancomycin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1rrv, PDBe:1rrv, PDBj:1rrv
PDBsum1rrv
PubMed15122882
UniProtQ9AFC7|GTFD_AMYOR Devancosaminyl-vancomycin vancosaminetransferase (Gene Name=gtfD)

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