Structure of PDB 1rrm Chain A

Receptor sequence
>1rrmA (length=385) Species: 562 (Escherichia coli) [Search protein sequence]
MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQCGVVAKV
TDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIGGGSPQ
DTCKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTIN
YVITDEEKRRKFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHA
IEGYITRGAWALTDALHIKAIEIIAGALRGSVAGDKDAGEEMALGQYVAG
MGFSNVGLGLVHGMAHPLGAFYNTPHGVANAILLPHVMRYNADFTGEKYR
DIARVMGVKVEGMSLEEARNAAVEAVFALNRDVGIPPHLRDVGVRKEDIP
ALAQAALDDVCTGGNPREATLEDIVELYHTAWEGG
3D structure
PDB1rrm Crystal structure of Lactaldehyde reductase
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.77: lactaldehyde reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D196 H200 H263 H277 D195 H199 H262 H276
BS02 FE2 A L259 C362 L258 C361
BS03 APR A D39 T41 L42 N71 G97 G98 S99 T140 T141 T144 V153 K162 G184 M185 L189 H277 D38 T40 L41 N70 G96 G97 S98 T139 T140 T143 V152 K161 G183 M184 L188 H276
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004022 alcohol dehydrogenase (NAD+) activity
GO:0008198 ferrous iron binding
GO:0008912 lactaldehyde reductase activity
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0052660 R-lactaldehyde reductase activity
GO:0052661 S-lactaldehyde reductase activity
Biological Process
GO:0006004 fucose metabolic process
GO:0019301 rhamnose catabolic process
GO:0019317 fucose catabolic process
GO:0042355 L-fucose catabolic process
GO:0042846 glycol catabolic process
GO:0051143 propanediol metabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1rrm, PDBe:1rrm, PDBj:1rrm
PDBsum1rrm
PubMed
UniProtP0A9S1|FUCO_ECOLI Lactaldehyde reductase (Gene Name=fucO)

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