Structure of PDB 1rp0 Chain A

Receptor sequence
>1rp0A (length=278) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
YDLNAFTFDPIKESIVSREMTRRYMTDMITYAETDVVVVGAGSAGLSAAY
EISKNPNVQVAIIEQSVSPGGGAWLGGQLFSAMIVRKPAHLFLDEIGVAY
DEQDTYVVVKHAALFTSTIMSKLLARPNVKLFNAVAAEDLIVKGNRVGGV
VTNWALVAQNHHTQSCMDPNVMEAKIVVSSCGHDGPFGATGVKRLKSIGM
IDHVPGMKALDMNTAEDAIVRLTREVVPGMIVTGMEVAEIDGAPRMGPTF
GAMMISGQKAGQLALKALGLPNAIDGTL
3D structure
PDB1rp0 Structure of the thiazole biosynthetic enzyme THI1 from Arabidopsis thaliana.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.60: cysteine-dependent adenosine diphosphate thiazole synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H189 D190 H183 D184
BS02 AHZ A V45 G46 G48 A50 E70 Q71 G77 G78 A143 S186 C187 G188 H189 D190 F193 T196 G240 M241 R251 G253 M259 V39 G40 G42 A44 E64 Q65 G71 G72 A137 S180 C181 G182 H183 D184 F187 T190 G234 M235 R245 G247 M253
Gene Ontology
Biological Process
GO:0009228 thiamine biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:1rp0, PDBe:1rp0, PDBj:1rp0
PDBsum1rp0
PubMed16912043
UniProtQ38814|THI4_ARATH Thiamine thiazole synthase, chloroplastic (Gene Name=THI1)

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