Structure of PDB 1rlw Chain A

Receptor sequence
>1rlwA (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
SSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNN
DINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVG
EKKEVPFIFNQVTEMVLEMSLEVASS
3D structure
PDB1rlw Crystal structure of a calcium-phospholipid binding domain from cytosolic phospholipase A2.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.4: phospholipase A2.
3.1.1.5: lysophospholipase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A D40 T41 D43 N65 D25 T26 D28 N50
BS02 CA A D40 D43 D93 A94 N95 D25 D28 D78 A79 N80
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0008289 lipid binding

View graph for
Molecular Function
External links
PDB RCSB:1rlw, PDBe:1rlw, PDBj:1rlw
PDBsum1rlw
PubMed9430701
UniProtP47712|PA24A_HUMAN Cytosolic phospholipase A2 (Gene Name=PLA2G4A)

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