Structure of PDB 1rl4 Chain A

Receptor sequence
>1rl4A (length=154) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
KIVKYPDPILRRRSEEVTNFDDNLKRVVRKMFDIMYESKGIGLSAPQVNI
SKRIIVWNRIFINPSIVEQSLVKLKLIEGCLSFPGIEGKVERPSIVSISY
YDINGYKHLKILKGIHSRIFQHEFDHLNGTLFIDKMTQVDKKKVRPKLNE
LIRD
3D structure
PDB1rl4 An improved crystal form of Plasmodium falciparum peptide deformylase.
ChainA
Resolution2.18 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G107 Q112 C156 L157 H198 E199 H202
Catalytic site (residue number reindexed from 1) G42 Q47 C80 L81 H122 E123 H126
Enzyme Commision number 3.5.1.88: peptide deformylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO A Q112 C156 H198 H202 Q47 C80 H122 H126
BS02 BRR A G105 I106 G107 Q112 C156 L157 H198 E199 H202 G40 I41 G42 Q47 C80 L81 H122 E123 H126
BS03 BL5 A L152 I153 G190 I191 L76 I77 G114 I115 MOAD: ic50=130nM
Gene Ontology
Molecular Function
GO:0042586 peptide deformylase activity

View graph for
Molecular Function
External links
PDB RCSB:1rl4, PDBe:1rl4, PDBj:1rl4
PDBsum1rl4
PubMed15010544
UniProtQ8I372

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