Structure of PDB 1rkv Chain A

Receptor sequence
>1rkvA (length=206) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
DMEIACLDLEGVLVPEIWIAFAEKTGIDALKATTRDIPDYDVLMKQRLRI
LDEHGLKLGDIQEVIATLKPLEGAVEFVDWLRERFQVVILSDTFYEFSQP
LMRQLGFPTLLCHKLEIDDSDRVVGYQLRQKDPKRQSVIAFKSLYYRVIA
AGDSYNDTTMLSEAHAGILFHAPENVIREFPQFPAVHTYEDLKREFLKAS
SRSLSL
3D structure
PDB1rkv The thrH Gene Product of Pseudomonas aeruginosa Is a Dual Activity Enzyme with a Novel Phosphoserine:Homoserine Phosphotransferase Activity.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.3: phosphoserine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 A D7 E9 S90 D91 K133 D8 E10 S91 D92 K134
BS02 MG A D7 E9 D152 D8 E10 D153
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004413 homoserine kinase activity
GO:0016787 hydrolase activity
GO:0036424 L-phosphoserine phosphatase activity
GO:0043899 phosphoserine:homoserine phosphotransferase activity
GO:0046820 4-amino-4-deoxychorismate synthase activity
GO:0046872 metal ion binding
Biological Process
GO:0006564 L-serine biosynthetic process
GO:0009088 threonine biosynthetic process
GO:0016311 dephosphorylation
GO:0046654 tetrahydrofolate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1rkv, PDBe:1rkv, PDBj:1rkv
PDBsum1rkv
PubMed14699121
UniProtQ9I2Y2|THRH_PSEAE Phosphoserine phosphatase ThrH (Gene Name=thrH)

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