Structure of PDB 1rkj Chain A

Receptor sequence
>1rkjA (length=175) Species: 10036 (Mesocricetus auratus) [Search protein sequence]
GSHMVEGSESTTPFNLFIGNLNPNKSVAELKVAISELFAKNDLAVVDVRT
GTNRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRAAR
TLLAKNLSFNITEDELKEVFEDALEIRLVSQDGKSKGIAYIEFKSEADAE
KNLEEKQGAEIDGRSVSLYYTGEKG
3D structure
PDB1rkj Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A F17 R49 T52 F56 Y58 K89 R91 D92 K94 K95 L103 K105 R127 V129 K136 I138 Y140 F17 R49 T52 F56 Y58 K89 R91 D92 K94 K95 L103 K105 R127 V129 K136 I138 Y140 PDBbind-CN: Kd=1.1uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:1rkj, PDBe:1rkj, PDBj:1rkj
PDBsum1rkj
PubMed15033352
UniProtP08199|NUCL_MESAU Nucleolin (Gene Name=NCL)

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