Structure of PDB 1rjg Chain A

Receptor sequence
>1rjgA (length=291) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
TDYDALSCKLAAISVGYLPSSGLQRLSVDLSKKYTEWHRSYLITLKKFSR
RAFGKVDKAMRSSFPVMNYGTYLRTVGIDAAILEFLVANEKVQVVNLGCG
SDLRMLPLLQMFPHLAYVDIDYNESVELKNSILRESEILRISLGLSKEDT
AKSPFLIDQGRYKLAACDLNDITETTRLLDVCTKREIPTIVISECLLCYM
HNNESQLLINTIMSKFSHGLWISYDPIKEKYASRWSAAPNVIVNDMWEIF
NAQIPESERKRLRSLQFLDELEELKVMQTHYILMKAQWHHH
3D structure
PDB1rjg Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity
ChainA
Resolution2.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.233: [phosphatase 2A protein]-leucine-carboxy methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A D9 A12 G105 C106 D128 Y129 L176 E201 L203 D2 A5 G98 C99 D121 Y122 L169 E194 L196
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity
Biological Process
GO:0010506 regulation of autophagy
GO:0032259 methylation
GO:0065003 protein-containing complex assembly
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1rjg, PDBe:1rjg, PDBj:1rjg
PDBsum1rjg
PubMed14660564
UniProtQ04081|LCMT1_YEAST Leucine carboxyl methyltransferase 1 (Gene Name=PPM1)

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