Structure of PDB 1rj5 Chain A

Receptor sequence
>1rj5A (length=259) Species: 10090 (Mus musculus) [Search protein sequence]
HHWTYEGPHGQDHWPTSYPECGGDAQSPINIQTDSVIFDPDLPAVQPHGY
DQLGTEPLDLHNNGHTVQLSLPPTLHLGGLPRKYTAAQLHLHWGQRGSLE
GSEHHINSEATAAELHVVHYDSQSYSSLSEAAQKPQGLAVLGILIEVGET
ENPAYDHILSRLHEIRYKDQKTSVPPFSVRELFPQQLEQFFRYNGSLTTP
PCYQSVLWTVFNRRAQISMGQLEKLQETLSSTEEDPSEPLVQNYRVPQPL
NQRTIFASF
3D structure
PDB1rj5 Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes.
ChainA
Resolution2.81 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H64 H94 H96 E106 H119 T199
Catalytic site (residue number reindexed from 1) H65 H90 H92 E103 H116 T198
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H94 H96 H119 H90 H92 H116
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:1rj5, PDBe:1rj5, PDBj:1rj5
PDBsum1rj5
PubMed14660577
UniProtQ9WVT6|CAH14_MOUSE Carbonic anhydrase 14 (Gene Name=Ca14)

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