Structure of PDB 1ram Chain A

Receptor sequence
>1ramA (length=273) Species: 10090 (Mus musculus) [Search protein sequence]
PYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTG
PGTVRISLVTKDPPHRPHPHELVGKDCRDGYYEADLCPDRSIHSFQNLGI
QCVKKRDLEQAISQRIQTNNNPFHVPIEEQRGDYDLNAVRLCFQVTVRDP
AGRPLLLTPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDK
VQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRV
SMQLRRPSDRELSEPMEFQYLPD
3D structure
PDB1ram A novel DNA recognition mode by the NF-kappa B p65 homodimer.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y36 C38 K122 K123 R187 K218 R246 Q247 Y18 C20 K104 K105 R169 K200 R228 Q229
BS02 dna A R33 R35 A43 G44 R15 R17 A25 G26
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ram, PDBe:1ram, PDBj:1ram
PDBsum1ram
PubMed9437432
UniProtQ04207|TF65_MOUSE Transcription factor p65 (Gene Name=Rela)

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