Structure of PDB 1r5o Chain A

Receptor sequence
>1r5oA (length=409) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
TEDATDLQNEVDQELLKDMYGKEHVNIVFIGHVDAGKSTLGGNILFLTGM
VDKRTMEKIEREAKERAYFETEHRRFSLLDAPGASQADIGVLVISARRGE
FEAGFERGGQTREHAVLARTQGINHLVVVINKMDEPSVQWSEERYKECVD
KLSMFLRRVAGYNSKTDVKYMPVSAYTGQNVKDRVDSSVCPWYQGPSLLE
YLDSMTHLERKVNAPFIMPIASKYKDLGTILEGKIEAGSIKKNSNVLVMP
INQTLEVTAIYDEADEEISSSICGDQVRLRVRGDDSDVQTGYVLTSTKNP
VHATTRFIAQIAILELPSILTTGYSCVMHIHTAVEEVSFAKLLHKLDKTN
RKSKKPPMFATKGMKIIAELETQTPVCMERFEDYQYMGRFTLRDQGTTVA
VGKVVKILD
3D structure
PDB1r5o Crystal structure and functional analysis of the eukaryotic class II release factor eRF3 from S. pombe
ChainA
Resolution3.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D248 K251 S252
Catalytic site (residue number reindexed from 1) D34 K37 S38
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A H246 V247 D248 G250 K251 S252 T253 K385 E388 Y429 H32 V33 D34 G36 K37 S38 T39 K132 E135 Y176
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0006415 translational termination

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Molecular Function
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Biological Process
External links
PDB RCSB:1r5o, PDBe:1r5o, PDBj:1r5o
PDBsum1r5o
PubMed15099522
UniProtO74718|ERF3_SCHPO Eukaryotic peptide chain release factor GTP-binding subunit (Gene Name=sup35)

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