Structure of PDB 1r5a Chain A

Receptor sequence
>1r5aA (length=214) Species: 123217 (Anopheles cracens) [Search protein sequence]
TTVLYYLPASPPCRSVLLLAKMIGVELDLKVLNIMEGEQLKPDFVELNPQ
HCIPTMDDHGLVLWESRVILSYLVSAYGKDENLYPKDFRSRAIVDQRLHF
DLGTLYQRVVDYYFPTIHLGAHLDQTKKAKLAEALGWFEAMLKQYQWSAA
NHFTIADIALCVTVSQIEAFQFDLHPYPRVRAWLLKCKDELEGHGYKEIN
ETGAETLAGLFRSK
3D structure
PDB1r5a Identification, characterization and structure of a new Delta class glutathione transferase isoenzyme.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S11
Catalytic site (residue number reindexed from 1) S10
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A T2 H60 T1 H59
BS02 GTS A S11 P13 I35 Q40 H52 C53 I54 E66 S67 S10 P12 I34 Q39 H51 C52 I53 E65 S66
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006749 glutathione metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1r5a, PDBe:1r5a, PDBj:1r5a
PDBsum1r5a
PubMed15717864
UniProtQ9GQG7

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