Structure of PDB 1r4o Chain A

Receptor sequence
>1r4oA (length=80) Species: 10116 (Rattus norvegicus) [Search protein sequence]
MKPARPCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCI
IDKIRRKNCPACRYRKCLQAGMNLEARKTK
3D structure
PDB1r4o Crystallographic Analysis of the Interaction of The Glucocorticoid Receptor with DNA
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A C450 H451 Y452 K461 K511 C17 H18 Y19 K28 K78
BS02 dna A R466 R489 K490 R496 R33 R56 K57 R63
BS03 ZN A C440 C443 C7 C10
BS04 ZN A C476 C492 C495 C43 C59 C62
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1r4o, PDBe:1r4o, PDBj:1r4o
PDBsum1r4o
PubMed1865905
UniProtP06536|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)

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