Structure of PDB 1r2f Chain A

Receptor sequence
>1r2fA (length=283) [Search protein sequence]
ISAINWNKIQDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSAAEQQL
TIRVFTGLTLLDTIQNIAGAPSLMADAITPHEEAVLSNISFMEAVHARSY
SSIFSTLCQTKEVDAAYAWSEENPPLQRKAQIILAHYVSDEPLKKKIASV
FLESFLFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQI
ALQKLSAIEREELKLFALDLLMELYDNEIRYTEALYAETGWVNDVKAFLC
YNANKALMNLGYEALFPPEMADVNPAILAALSP
3D structure
PDB1r2f Structure of Salmonella typhimurium nrdF ribonucleotide reductase in its oxidized and reduced forms.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.4.1: ribonucleoside-diphosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE A D67 E98 H101 E192 D62 E93 H96 E187
BS02 FE A E98 E158 E192 H195 E93 E153 E187 H190
Gene Ontology
Molecular Function
GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0009263 deoxyribonucleotide biosynthetic process
Cellular Component
GO:0005971 ribonucleoside-diphosphate reductase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1r2f, PDBe:1r2f, PDBj:1r2f
PDBsum1r2f
PubMed9748343
UniProtP17424|RIR4_SALTY Ribonucleoside-diphosphate reductase 2 subunit beta (Gene Name=nrdF)

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