Structure of PDB 1qvj Chain A

Receptor sequence
>1qvjA (length=292) Species: 9606 (Homo sapiens) [Search protein sequence]
ENSHNKARTSPYPGSKVERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGP
RWADPQISESNFSPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVG
RGLLGRWGPNHAADPIITRWKRDSSGNKIMHPVSGKHILQFVAIKRKDCG
EWAIPGGMVDPGEKISATLKREFGEEALNSLQKTSAEKREIEEKLHKLFS
QDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLMLEAGDDAGK
VKWVDINDKLKLYASHSQFIKLVAEKRDAHWSEDSEADCHAL
3D structure
PDB1qvj The crystal structure and mutational analysis of human NUDT9
ChainA
Resolution1.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.13: ADP-ribose diphosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 RP5 A A170 D172 R204 R273 Y321 H324 A112 D114 R146 R215 Y263 H266
Gene Ontology
Molecular Function
GO:0047631 ADP-ribose diphosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:1qvj, PDBe:1qvj, PDBj:1qvj
PDBsum1qvj
PubMed12948489
UniProtQ9BW91|NUDT9_HUMAN ADP-ribose pyrophosphatase, mitochondrial (Gene Name=NUDT9)

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