Structure of PDB 1qsf Chain A

Receptor sequence
>1qsfA (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQADGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRW
3D structure
PDB1qsf Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 Y59 E63 K66 V67 T73 D77 L81 Y84 Y99 Y116 T143 K146 W147 L156 Y159 W167 Y171 Y7 Y59 E63 K66 V67 T73 D77 L81 Y84 Y99 Y116 T143 K146 W147 L156 Y159 W167 Y171
External links
PDB RCSB:1qsf, PDBe:1qsf, PDBj:1qsf
PDBsum1qsf
PubMed10435578
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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