Structure of PDB 1qs8 Chain A

Receptor sequence
>1qs8A (length=327) Species: 5855 (Plasmodium vivax) [Search protein sequence]
SENDVIELDDVANIMFYGEGEVGDNHQKFMLIFDTGSANLWVPSKKCNSS
GCSIKNLYDSSKSKSYEKDGTKVDITYGSGTVKGFFSKDLVTLGHLSMPY
KFIEVIDTDDLEPIYSSVEFDGILGLGWKDLSIGSIDPIVVELKNQNKID
NALFTFYLPVHDVHAGYLTIGGIEEKFYEGNITYEKLNHDLYWQIDLDVH
FGKQTMEKANVIVDSGTTTITAPSEFLNKFFANLNVIKVPFLPFYVTTCD
NKEMPTLEFKSANNTYTLEPEYYMNPILEVDDTLCMITMLPVDIDSNTFI
LGDPFMRKYFTVFDYDKESVGFAIAKN
3D structure
PDB1qs8 Structural insights into the activation of P. vivax plasmepsin.
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D34 S37 N39 W41 Y77 D214 T217
Catalytic site (residue number reindexed from 1) D34 S37 N39 W41 Y77 D214 T217
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A D34 G36 T76 Y77 G78 S79 Y192 D214 G216 T217 T218 T219 D34 G36 T76 Y77 G78 S79 Y192 D214 G216 T217 T218 T219
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:1qs8, PDBe:1qs8, PDBj:1qs8
PDBsum1qs8
PubMed12767832
UniProtO60989

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