Structure of PDB 1qrr Chain A

Receptor sequence

>1qrrA (length=390) Species: 3702 (Arabidopsis thaliana)

KRVMVIGGDGYCGWATALHLSKKNYEVCIVDNLVRRLFDHQLGLESLTPI
ASIHDRISRWKALTGKSIELYVGDICDFEFLAESFKSFEPDSVVHFGEQR
SAPYSMIDRSRAVYTQHNNVIGTLNVLFAIKEFGEECHLVKLGTMGEYGT
PNIDIEEGYITITHNGRTDTLPYPKQASSFYHLSKVHDSHNIAFTCKAWG
IRATDLNQGVVYGVKTDETEMHEELRNRLDYDAVFGTALNRFCVQAAVGH
PLTVYGKGGQTRGYLDIRDTVQCVEIAIANPAKAGEFRVFNQFTEQFSVN
ELASLVTKAGSKLGLDVKKMTVPNPRVEAEEHYYNAKHTKLMELGLEPHY
LSDSLLDSLLNFAVQFKDRVDTKQIMPSVSWKKIGVKTKS

3D structure

• PDB: 1qrr Crystal structure of SQD1, an enzyme involved in the biosynthesis of the plant sulfolipid headgroup donor UDP-sulfoquinovose.
• Chain: A
• Resolution: 1.6 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): T145 I154 D155 I156 S180 Y182 H183 K186
• Catalytic site (residue number reindexed from 1): T144 I153 D154 I155 S179 Y181 H182 K185
• Enzyme Commision number: 3.13.1.1: UDP-sulfoquinovose synthase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAD	A	G8 G11 Y12 C13 D32 N33 L34 V35 R36 D75 I76 F97 G98 R101 N119 L143 Y182 K186 Q209 G210 V212	G7 G10 Y11 C12 D31 N32 L33 V34 R35 D74 I75 F96 G97 R100 N118 L142 Y181 K185 Q208 G209 V211
BS02	UPG	A	R101 T145 Y182 Q209 T238 A239 R242 T254 Y256 Q261 V300 R327 E329	R100 T144 Y181 Q208 T237 A238 R241 T253 Y255 Q260 V299 R326 E328

External links

• PDB: RCSB:1qrr, PDBe:1qrr, PDBj:1qrr
• PDBsum: 1qrr
• PubMed: 10557279
• UniProt: O48917|SQD1_ARATH UDP-sulfoquinovose synthase, chloroplastic (Gene Name=SQD1)