Structure of PDB 1qrm Chain A

Receptor sequence
>1qrmA (length=209) Species: 2210 (Methanosarcina thermophila) [Search protein sequence]
VDEFSNIRENPVTPWNPEPSAPVIDPTAYIDPQASVIGEVTIGANVMVSP
MASIRSDEGMPIFVGDRSNVQDGVVLHALETINEEGEPIEDNIVEVDGKE
YAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGNNCVLEPRS
AAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNVH
LAEGYKETS
3D structure
PDB1qrm A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.
ChainA
Resolution1.95 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E62 Q75 H81 E84 H117 H122 N202
Catalytic site (residue number reindexed from 1) E58 Q71 H77 E80 H113 H118 N198
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H81 H122 H77 H118
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0043199 sulfate binding
GO:0046872 metal ion binding
GO:0050897 cobalt ion binding
GO:0071890 bicarbonate binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1qrm, PDBe:1qrm, PDBj:1qrm
PDBsum1qrm
PubMed10924115
UniProtP40881|CAH_METTT Carbonic anhydrase (Gene Name=MSTHT_0588)

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