Structure of PDB 1qre Chain A

Receptor sequence
>1qreA (length=210) Species: 2210 (Methanosarcina thermophila) [Search protein sequence]
TVDEFSNIRENPVTPWNPEPSAPVIDPTAYIDPQASVIGEVTIGANVMVS
PMASIRSDEGMPIFVGDRSNVQDGVVLHALETINEEGEPIEDNIVEVDGK
EYAVYIGNNVSLAHQSQVHGPAAVGDDTFIGMQAFVFKSKVGNNCVLEPR
SAAIGVTIPDGRYIPAGMVVTSQAEADKLPEVTDDYAYSHTNEAVVYVNV
HLAEGYKETS
3D structure
PDB1qre A closer look at the active site of gamma-class carbonic anhydrases: high-resolution crystallographic studies of the carbonic anhydrase from Methanosarcina thermophila.
ChainA
Resolution1.46 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E62 Q75 H81 E84 H117 H122 N202
Catalytic site (residue number reindexed from 1) E59 Q72 H78 E81 H114 H119 N199
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BCT A E62 H81 E59 H78 BindingDB: Ki=42000000nM
BS02 CO A H81 H122 H78 H119
External links
PDB RCSB:1qre, PDBe:1qre, PDBj:1qre
PDBsum1qre
PubMed10924115
UniProtP40881|CAH_METTT Carbonic anhydrase (Gene Name=MSTHT_0588)

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