Structure of PDB 1qnh Chain A

Receptor sequence
>1qnhA (length=169) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
KRSKVFFDISIDNSNAGRIIFELFSDITPRTCENFRALCTGEKIGSRGKN
LHYKNSIFHRIIPQFMCQGGDITNGNGSGGESIYGRSFTDENFNMKHDQP
GLLSMANAGPNTNSSQFLITLVPCPWLDGKHVVFGKVIEGMNVVREMEKE
GAKSGYVKRSVVITDCGEW
3D structure
PDB1qnh The Three-Dimensional Structure of a Plasmodium Falciparum Cyclophilin in Complex with the Potent Anti-Malarial Cyclosporin A
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R62 F67 Q70 N109 L120 L129 H133
Catalytic site (residue number reindexed from 1) R60 F65 Q68 N107 L118 L127 H131
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R62 F67 M68 Q70 G79 A108 N109 Q118 L120 W128 H133 R60 F65 M66 Q68 G77 A106 N107 Q116 L118 W126 H131
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:1qnh, PDBe:1qnh, PDBj:1qnh
PDBsum1qnh
PubMed10756109
UniProtQ25756

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