Structure of PDB 1qng Chain A

Receptor sequence
>1qngA (length=170) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
SKRSKVFFDISIDNSNAGRIIFELFSDITPRTCENFRALCTGEKIGSRGK
NLHYKNSIFHRIIPQFMCQGGDITNGNGSGGESIYGRSFTDENFNMKHDQ
PGLLSMANAGPNTNSSQFFITLVPCPWLDGKHVVFGKVIEGMNVVREMEK
EGAKSGYVKRSVVITDCGEL
3D structure
PDB1qng The Three-Dimensional Structure of a Plasmodium Falciparum Cyclophilin in Complex with the Potent Anti-Malarial Cyclosporin A
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R62 F67 Q70 N109 F120 L129 H133
Catalytic site (residue number reindexed from 1) R61 F66 Q69 N108 F119 L128 H132
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R62 F67 M68 Q70 G79 A108 N109 Q118 F120 W128 H133 R61 F66 M67 Q69 G78 A107 N108 Q117 F119 W127 H132
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding

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Molecular Function
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Biological Process
External links
PDB RCSB:1qng, PDBe:1qng, PDBj:1qng
PDBsum1qng
PubMed10756109
UniProtQ25756

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