Structure of PDB 1qmf Chain A

Receptor sequence
>1qmfA (length=559) Species: 1313 (Streptococcus pneumoniae) [Search protein sequence]
TVPAKRGTIYDRNGVPIAEDATSPNRSYPNGQFASSFIGLAQLHENEDGS
KSLLGTSGMESSLNSILAGTDGIIRTMDGKDVYTTISSPLQSFMETQMDA
FQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILY
QSNYEPGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEG
LTGGRMMTFSQGFAHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGL
TDEYAGQLPADNIVNIAQSSFGQGISVTQTQMIRAFTAIANDGVMLEPKF
ISAIYDPNDQTARKSQKEIVGNPVSKDAASLTRTNMVLVGTDPVYGTMYN
HSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLTDYIFSAVSMSPAE
NPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQSPYPMPSV
KDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAPNQQVLILSD
KAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKDI
KKITLTLGD
3D structure
PDB1qmf The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CES A S337 W374 S395 F450 Q452 S548 G549 T550 Q552 S158 W195 S216 F271 Q273 S369 G370 T371 Q373
BS02 KEF A V423 P424 R426 V662 V244 P245 R247 V471
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0046677 response to antibiotic
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1qmf, PDBe:1qmf, PDBj:1qmf
PDBsum1qmf
PubMed10860753
UniProtP14677|PBPX_STRPN Penicillin-binding protein 2x (Gene Name=pbpX)

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