Structure of PDB 1qji Chain A

Receptor sequence
>1qjiA (length=200) Species: 6715 (Astacus astacus) [Search protein sequence]
AAILGDEYLWSGGVIPYTFAGVSGADQSAILSGMQELEEKTCIRFVPRTT
ESDYVEIFTSGSGCWSYVGRISGAQQVSLQANGCVYHGTIIHELMHAIGF
YHEHTRMDRDNYVTINYQNVDPSMTSNFDIDTYSRYVGEDYQYYSIMHYG
KYSFSIQWGVLETIVPLQNGIDLTDPYDKAHMLQTDANQINNLYTNECSL
3D structure
PDB1qji Structure of Astacin with a Transition-State Analogue Inhibitor
ChainA
Resolution2.14 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H92 E93 H96 H102 Y149
Catalytic site (residue number reindexed from 1) H92 E93 H96 H102 Y149
Enzyme Commision number 3.4.24.21: astacin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H92 H96 H102 H92 H96 H102
BS02 PKF A C64 W65 S66 Y67 H92 E93 H96 H102 Y149 D175 C64 W65 S66 Y67 H92 E93 H96 H102 Y149 D175 MOAD: Ki=14uM
PDBbind-CN: -logKd/Ki=4.85,Ki=14uM
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1qji, PDBe:1qji, PDBj:1qji
PDBsum1qji
PubMed8756323
UniProtP07584|ASTA_ASTAS Astacin

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