Structure of PDB 1qhs Chain A

Receptor sequence
>1qhsA (length=178) Species: 54571 (Streptomyces venezuelae) [Search protein sequence]
MTTRMIILNGGSSAGKSGIVRCLQSVLPEPWLAFGVDSLIEAMPLKMQSA
EGGIEFDADGGVSIGPEFRALEGAWAEGVVAMARAGARIIIDDVFLGGAA
AQERWRSFVGDLDVLWVGVRCDGAVAEGRETARGDRVAGMAAKQAYVVHE
GVEYDVEVDTTHKESIECAWAIAAHVVP
3D structure
PDB1qhs The Crystal Structures of Chloramphenicol Phosphotransferase Reveal a Novel Inactivation Mechanism
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 A S13 G15 K16 S17 R133 S13 G15 K16 S17 R133
BS02 CLM A V36 D37 I40 V94 L96 R136 M140 Q144 V36 D37 I40 V94 L96 R136 M140 Q144
BS03 CLM A P44 K46 M47 A50 E67 P44 K46 M47 A50 E67
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
Biological Process
GO:0016310 phosphorylation
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:1qhs, PDBe:1qhs, PDBj:1qhs
PDBsum1qhs
PubMed10835366
UniProtQ56148|CPT_STRVP Chloramphenicol 3-O phosphotransferase (Gene Name=SVEN_4064)

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