Structure of PDB 1qd1 Chain A

Receptor sequence
>1qd1A (length=319) Species: 9823 (Sus scrofa) [Search protein sequence]
SQLVECVPNFSEGKNQEVIDAISRAVAQTPGCVLLDVDSGPSTNRTVYTF
VGRPEDVVEGALNAARAAYQLIDMSRHHGEHPRMGALDVCPFIPVRGVTM
DECVRCAQAFGQRLAEELGVPVYLYGEAARTAGRQSLPALRAGEYEALPE
KLKQAEWAPDFGPSAFVPSWGATVAGARKFLLAFNINLLSTREQAHRIAL
DLREQGGRLKKVQAIGWYLDEKNLAQVSTNLLDFEVTGLHTVFEETCREA
QELSLPVVGSQLVGLVPLKALLDAAAFYCEKENLFLLQDEHRIRLVVNRL
GLDSLAPFKPKERIIEYLV
3D structure
PDB1qd1 The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme.
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H82
Catalytic site (residue number reindexed from 1) H81
Enzyme Commision number 2.1.2.5: glutamate formimidoyltransferase.
4.3.1.4: formimidoyltetrahydrofolate cyclodeaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FON A N10 D39 S40 G41 T44 R46 V48 H82 Y126 R142 R179 L182 N186 W224 N237 Q268 N9 D38 S39 G40 T43 R45 V47 H81 Y125 R141 R178 L181 N185 W217 N230 Q261
BS02 GOL A H82 Q220 A221 I222 S235 H81 Q213 A214 I215 S228
Gene Ontology
Molecular Function
GO:0005542 folic acid binding
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:1qd1, PDBe:1qd1, PDBj:1qd1
PDBsum1qd1
PubMed10673422
UniProtP53603|FTCD_PIG Formimidoyltransferase-cyclodeaminase (Gene Name=FTCD)

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