Structure of PDB 1qbj Chain A

Receptor sequence
>1qbjA (length=65) Species: 9606 (Homo sapiens) [Search protein sequence]
SIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKG
KLQKEAGTPPLWKIA
3D structure
PDB1qbj Crystal structure of the Zalpha domain of the human editing enzyme ADAR1 bound to left-handed Z-DNA.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A K169 K170 N173 R174 Y177 T191 P192 P193 K36 K37 N40 R41 Y44 T58 P59 P60
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:1qbj, PDBe:1qbj, PDBj:1qbj
PDBsum1qbj
PubMed10364558
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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