Structure of PDB 1qb8 Chain A

Receptor sequence
>1qb8A (length=236) Species: 5661 (Leishmania donovani) [Search protein sequence]
PFKEVSPNSFLLDDSHALSQLLKKSYRWYSPVFSPRNVPRFADVSSITES
PETLKAIRDFLVQRYRAMSPAPTHILGFDARGFLFGPMIAVELEIPFVLM
RKADKNAGLLIRSEPYEKEYKEAAPEVMTIRYGSIGKGSRVVLIDDVLAT
GGTALSGLQLVEASDAVVVEMVSILSIPFLKAAEKIHSTANSRYKDIKFI
SLLSDDALTEENCGDSKNYTGPRVLSCGDVLAEHPH
3D structure
PDB1qb8 Crystal structures of adenine phosphoribosyltransferase from Leishmania donovani.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R82 E120
Catalytic site (residue number reindexed from 1) R81 E119
Enzyme Commision number 2.4.2.7: adenine phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D146 T154 D145 T153
BS02 AMP A F42 A43 R82 D146 V148 A150 T151 G152 T154 F41 A42 R81 D145 V147 A149 T150 G151 T153
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003999 adenine phosphoribosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1qb8, PDBe:1qb8, PDBj:1qb8
PDBsum1qb8
PubMed10393170
UniProtQ27679

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