Structure of PDB 1q97 Chain A

Receptor sequence
>1q97A (length=351) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
YHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDK
VYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVV
MVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHT
DIKPENVLMEIVDSPENLIQIKIADLGNACWYDEHYTNSIQTREYRSPEV
LLGAPWGCGADIWSTACLIFELITGDFLFKDDDHIAQIIELLGELPSYLL
RNGKYTRTFFNSLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPM
LQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIPGWFEEV
R
3D structure
PDB1q97 Nucleotide-Induced Conformational Changes in the Saccharomyces cerevisiae SR Protein Kinase, Sky1p, Revealed by X-ray Crystallography
ChainA
Resolution2.3 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D294 K296 N299 D550 T567
Catalytic site (residue number reindexed from 1) D151 K153 N156 D175 T192
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G167 V172 A185 K187 E247 L249 L301 D550 G24 V29 A42 K44 E104 L106 L158 D175
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1q97, PDBe:1q97, PDBj:1q97
PDBsum1q97
PubMed12911299
UniProtQ03656|SKY1_YEAST Serine/threonine-protein kinase SKY1 (Gene Name=SKY1)

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