Structure of PDB 1q94 Chain A

Receptor sequence
>1q94A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB1q94 Structures of HLA-A*1101 complexed with immunodominant nonamer and decamer HIV-1 epitopes clearly reveal the presence of a middle, secondary anchor residue.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 Y9 E63 N66 V67 Q70 D77 Y84 Y99 R114 D116 T143 K146 W147 A150 A152 Q155 Q156 Y159 W167 Y171 Y7 Y9 E63 N66 V67 Q70 D77 Y84 Y99 R114 D116 T143 K146 W147 A150 A152 Q155 Q156 Y159 W167 Y171
External links
PDB RCSB:1q94, PDBe:1q94, PDBj:1q94
PDBsum1q94
PubMed15128805
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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