Structure of PDB 1q8y Chain A

Receptor sequence
>1q8yA (length=351) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
YHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDK
VYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVHVV
MVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHT
DIKPENVLMEIVDSPENLIQIKIADLGNACWYDEHYTNSIQTREYRSPEV
LLGAPWGCGADIWSTACLIFELITGDFLFKDDDHIAQIIELLGELPSYLL
RNGKYTRTFFNSLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPM
LQLDPRKRADAGGLVNHPWLKDTLGMEEIRVPDRELYGSGSDIPGWFEEV
R
3D structure
PDB1q8y Nucleotide-Induced Conformational Changes in the Saccharomyces cerevisiae SR Protein Kinase, Sky1p, Revealed by X-Ray Crystallography
ChainA
Resolution2.05 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D294 K296 N299 D550 T567
Catalytic site (residue number reindexed from 1) D151 K153 N156 D175 T192
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A N299 D550 N156 D175
BS02 ADP A G165 G167 F169 V172 A185 K187 L226 L249 N252 L301 D550 G22 G24 F26 V29 A42 K44 L83 L106 N109 L158 D175
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1q8y, PDBe:1q8y, PDBj:1q8y
PDBsum1q8y
PubMed12911299
UniProtQ03656|SKY1_YEAST Serine/threonine-protein kinase SKY1 (Gene Name=SKY1)

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