Structure of PDB 1q7t Chain A

Receptor sequence
>1q7tA (length=310) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
DIPTTENLYFQGAMSETPRLLFVHAHPDDESLSNGATIAHYTSRGAQVHV
VTCTLGEEGEVIGDRWAQLTADHADQLGGYRIGELTAALRALGVSAPIYL
GGAGRWRDSGMAGTDQRSQRRFVDADPRQTVGALVAIIRELRPHVVVTYD
PNGGYGHPDHVHTHTVTTAAVAAAGVGPGDPWTVPKFYWTVLGLSALISG
ARALVPDDLRPEWVLPRADEIAFGYSDDGIDAVVEADEQARAAKVAALAA
HATQVVVGPTGRAAALSNNLALPILADEHYVLAGGSAGARDERGWETDLL
AGLGFTASGT
3D structure
PDB1q7t Crystal Structure of MshB from Mycobacterium tuberculosis, a Deacetylase Involved in Mycothiol Biosynthesis.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.103: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BOG A Y-4 R31 D291 L293 Y9 R44 D298 L300
BS02 BOG A H13 E45 G46 R68 D95 G97 H144 H26 E58 G59 R81 D108 G110 H157
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0019213 deacetylase activity
GO:0035595 N-acetylglucosaminylinositol deacetylase activity
GO:0046872 metal ion binding
Biological Process
GO:0010125 mycothiol biosynthetic process
GO:0016137 glycoside metabolic process
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1q7t, PDBe:1q7t, PDBj:1q7t
PDBsum1q7t
PubMed14698305
UniProtP9WJN3|MSHB_MYCTU 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (Gene Name=mshB)

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