Structure of PDB 1q4j Chain A

Receptor sequence
>1q4jA (length=209) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
DNIVLYYFDARGKAELIRLIFAYLGIEYTDKRFGVNGDAFVEFKNFKKEK
DTPFEQVPILQIGDLILAQSQAIVRYLSKKYNICGESELNEFYADMIFCG
VQDIHYKFNNTNLFKQNETTFLNEDLPKWSGYFEKLLKKNHTNNNNDKYY
FVGNNLTYADLAVFNLYDDIETKYPSSLKNFPLLKAHNEFISNLPNIKNY
ITNRKESVY
3D structure
PDB1q4j Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y9 K15 R20
Catalytic site (residue number reindexed from 1) Y7 K13 R18
Enzyme Commision number 2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTX A Y9 F10 K15 F45 Q58 V59 Q71 S72 N111 Y7 F8 K13 F43 Q56 V57 Q69 S70 N109
BS02 GTX A F116 K117 E120 T121 F114 K115 E118 T119
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0016740 transferase activity

View graph for
Molecular Function
External links
PDB RCSB:1q4j, PDBe:1q4j, PDBj:1q4j
PDBsum1q4j
PubMed12972411
UniProtQ8ILQ7|GST_PLAF7 Glutathione S-transferase (Gene Name=GST)

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