Structure of PDB 1q43 Chain A

Receptor sequence
>1q43A (length=189) Species: 10090 (Mus musculus) [Search protein sequence]
DSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSIL
GELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGD
YIIREGTIGKKMYFIQHGVVSVLTEMKLSDGSYFGEICLLTRGRRTASVR
ADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDR
3D structure
PDB1q43 Structural basis for modulation and agonist specificity of HCN pacemaker channels
ChainA
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP A V564 M572 F580 G581 E582 I583 C584 R591 T592 R632 V122 M126 F134 G135 E136 I137 C138 R145 T146 R186
External links
PDB RCSB:1q43, PDBe:1q43, PDBj:1q43
PDBsum1q43
PubMed12968185
UniProtO88703|HCN2_MOUSE Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Gene Name=Hcn2)

[Back to BioLiP]