Structure of PDB 1q3n Chain A

Receptor sequence
>1q3nA (length=272) Species: 562 (Escherichia coli) [Search protein sequence]
MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGI
PYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPS
QAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGN
IVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDV
THALQRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEP
FLKQMKAIDDLVKGFEELDTSK
3D structure
PDB1q3n Crystal structures of Escherichia coli KDO8P synthase complexes reveal the source of catalytic irreversibility.
ChainA
Resolution2.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N26 K60 D250
Catalytic site (residue number reindexed from 1) N26 K60 D238
Enzyme Commision number 2.5.1.55: 3-deoxy-8-phosphooctulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PEP A K138 R168 H202 G251 P252 K138 R168 H202 G239 P240
Gene Ontology
Molecular Function
GO:0008676 3-deoxy-8-phosphooctulonate synthase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0009058 biosynthetic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0019294 keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0032991 protein-containing complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1q3n, PDBe:1q3n, PDBj:1q3n
PDBsum1q3n
PubMed16023668
UniProtP0A715|KDSA_ECOLI 2-dehydro-3-deoxyphosphooctonate aldolase (Gene Name=kdsA)

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