Structure of PDB 1q3e Chain A

Receptor sequence
>1q3eA (length=192) Species: 10090 (Mus musculus) [Search protein sequence]
DSSRRQYQEKYKQVEQYMSFHKLPADFRQKIHDYYEHRYQGKMFDEDSIL
GELNGPLREEIVNFNCRKLVASMPLFANADPNFVTAMLTKLKFEVFQPGD
YIIREGTIGKKMYFIQHGVVSVLTGNKEMKLSDGSYFGEICLLTRGRRTA
SVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLDR
3D structure
PDB1q3e Structural basis for modulation and agonist specificity of HCN pacemaker channels
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PCG A M572 F580 G581 E582 I583 C584 R591 T592 R632 M129 F137 G138 E139 I140 C141 R148 T149 R189
External links
PDB RCSB:1q3e, PDBe:1q3e, PDBj:1q3e
PDBsum1q3e
PubMed12968185
UniProtO88703|HCN2_MOUSE Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Gene Name=Hcn2)

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