Structure of PDB 1q1k Chain A

Receptor sequence
>1q1kA (length=288) Species: 562 (Escherichia coli) [Search protein sequence]
TRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVR
DDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGC
RLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGS
VEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEE
SKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTIL
PLAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
3D structure
PDB1q1k The structure of Escherichia coli ATP-phosphoribosyltransferase: identification of substrate binding sites and mode of AMP inhibition
ChainA
Resolution2.9 Å
3D
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Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PRT A R16 D55 D56 N75 V76 C104 Y131 E156 L170 S172 T173 G174 A175 T176 R12 D51 D52 N71 V72 C100 Y127 E152 L166 S168 T169 G170 A171 T172
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003879 ATP phosphoribosyltransferase activity
GO:0005524 ATP binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:1q1k, PDBe:1q1k, PDBj:1q1k
PDBsum1q1k
PubMed14741209
UniProtP60757|HIS1_ECOLI ATP phosphoribosyltransferase (Gene Name=hisG)

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