Structure of PDB 1q0r Chain A

Receptor sequence
>1q0rA (length=297) Species: 1924 (Streptomyces purpurascens) [Search protein sequence]
SERIVPSGDVELWSDDFGDPADPALLLVMGGNLSALGWPDEFARRLADGG
LHVIRYDHRDTGRSTTRDFAAHPYGFGELAADAVAVLDGWGVDRAHVVGL
SMGATITQVIALDHHDRLSSLTMLLGGGLDIDFDANIERVMRGEPTLDGL
PGPQQPFLDALALMNQPAEGRAAEVAKRVSKWRILSGTGVPFDDAEYARW
EERAIDHAGGVLAEPYAHYSLTLPPPSRAAELREVTVPTLVIQAEHDPIA
PAPHGKHLAGLIPTARLAEIPGMGHALPSSVHGPLAEVILAHTRSAA
3D structure
PDB1q0r Crystal structure of aclacinomycin methylesterase with bound product analogues: implications for anthracycline recognition and mechanism.
ChainA
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.95: aclacinomycin methylesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AKT A S102 M103 G128 F134 D135 F158 Y220 L224 I250 S101 M102 G127 F133 D134 F157 Y219 L223 I249
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004806 triacylglycerol lipase activity
GO:0016787 hydrolase activity
GO:0102530 aclacinomycin T methylesterase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:0046503 glycerolipid catabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1q0r, PDBe:1q0r, PDBj:1q0r
PDBsum1q0r
PubMed12878604
UniProtQ54528|RDMC_STREF Aclacinomycin methylesterase RdmC (Gene Name=rdmC)

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