Structure of PDB 1pzl Chain A

Receptor sequence
>1pzlA (length=227) Species: 9606 (Homo sapiens) [Search protein sequence]
LASLPSINALLQAEVLSRQITNGDIRAKKIASIADVCESMKEQLLVLVEW
AKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIV
PRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDPDAKG
LSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSITWQM
IEQIQFIKLFGMAKIDNLLQEMLLGGS
3D structure
PDB1pzl Structural Basis for HNF-4alpha Activation by Ligand and Coactivator Binding
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K194 L204 V208 R212 E363 G368 S369 K52 L62 V66 R70 E221 G226 S227
External links
PDB RCSB:1pzl, PDBe:1pzl, PDBj:1pzl
PDBsum1pzl
PubMed14982928
UniProtP41235|HNF4A_HUMAN Hepatocyte nuclear factor 4-alpha (Gene Name=HNF4A)

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